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Image Search Results


Journal: iScience

Article Title: Engineered FSHD mutations results in D4Z4 heterochromatin disruption and feedforward DUX4 network activation

doi: 10.1016/j.isci.2024.109357

Figure Lengend Snippet:

Article Snippet: The HMW gDNA was then tagged with a fluorescent probe at each DLE-1 (Direct Labeling Enzyme 1) enzyme binding site using the Direct Label and Stain (DLS) DNA Kit (Bionano Genomics).

Techniques: Virus, Recombinant, CRISPR, Blocking Assay, DNA Extraction, Purification, Methylation, Transfection, Labeling, Sequencing, Ligation, RNAscope, Multiplex Assay, Cloning, Control, Gene Expression, Plasmid Preparation, Software, Electrophoresis, Membrane, Microscopy